A Synthetic Triterpenoid CDDO-Im Inhibits Tumorsphere Formation by Regulating Stem Cell Signaling Pathways in Triple-Negative Breast Cancer

Triple-negative breast cancer is associated with poor prognosis because of a high rate of tumor recurrence and metastasis. Previous studies demonstrated that the synthetic triterpenoid, CDDO-Imidazolide (CDDO-Im) induced cell cycle arrest and apoptosis in triple-negative breast cancer. Since a small...

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Detalhes bibliográficos
Main Authors: So, Jae Young, Lin, Janice J., Wahler, Joseph, Liby, Karen T., Sporn, Michael B., Suh, Nanjoo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167992/
https://ncbi.nlm.nih.gov/pubmed/25229616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107616
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