(124)I-Labeled Engineered Anti-CEA Minibodies and Diabodies Allow High-Contrast, Antigen-Specific Small-Animal PET Imaging of Xenografts in Athymic Mice

Prolonged clearance kinetics have hampered the development of intact antibodies as imaging agents, despite their ability to effectively deliver radionuclides to tumor targets in vivo. Genetically engineered antibody fragments display rapid, high-level tumor uptake coupled with rapid clearance from t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sundaresan, Gobalakrishnan, Yazaki, Paul J., Shively, John E., Finn, Ronald D., Larson, Steven M., Raubitschek, Andrew A., Williams, Lawrence E., Chatziioannou, Arion F., Gambhir, Sanjiv S., Wu, Anna M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167879/
https://ncbi.nlm.nih.gov/pubmed/14660722
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares