Scale-up and manufacturing of clinical-grade self-inactivating γ-retroviral vectors by transient transfection

The need for γ-retroviral (gRV) vectors with a self-inactivating (SIN) design for clinical application has prompted a shift in methodology of vector manufacturing from the traditional use of stable producer lines to transient transfection-based techniques. Herein, we set out to define and optimize a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: van der Loo, JCM, Swaney, WP, Grassman, E, Terwilliger, A, Higashimoto, T, Schambach, A, Baum, C, Thrasher, AJ, Williams, DA, Nordling, DL, Reeves, L, Malik, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167414/
https://ncbi.nlm.nih.gov/pubmed/21753795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.102
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi