A Mammalian Circadian Clock Model Incorporating Daytime Expression Elements

Models of the mammalian clock have traditionally been based around two feedback loops—the self-repression of Per/Cry by interfering with activation by BMAL/CLOCK, and the repression of Bmal/Clock by the REV-ERB proteins. Recent experimental evidence suggests that the D-box, a transcription factor bi...

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Detalles Bibliográficos
Autores principales: Jolley, Craig C., Ukai-Tadenuma, Maki, Perrin, Dimitri, Ueda, Hiroki R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2014
Materias:
Systems Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167299/
https://ncbi.nlm.nih.gov/pubmed/25229153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.022
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