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Identification of a Novel Cryptochrome Differentiating Domain Required for Feedback Repression in Circadian Clock Function
Circadian clocks in mammals are based on a negative feedback loop in which transcriptional repression by the cryptochromes, CRY1 and CRY2, lies at the heart of the mechanism. Despite similarities in sequence, domain structure, and biochemical activity, they play distinct roles in clock function. How...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406676/ https://ncbi.nlm.nih.gov/pubmed/22692217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368001 |
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