Mass spectrometry-based absolute quantification reveals rhythmic variation of mouse circadian clock proteins

Absolute values of protein expression levels in cells are crucial information for understanding cellular biological systems. Precise quantification of proteins can be achieved by liquid chromatography (LC)–mass spectrometry (MS) analysis of enzymatic digests of proteins in the presence of isotope-la...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Narumi, Ryohei, Shimizu, Yoshihiro, Ukai-Tadenuma, Maki, Ode, Koji L., Kanda, Genki N., Shinohara, Yuta, Sato, Aya, Matsumoto, Katsuhiko, Ueda, Hiroki R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914154/
https://ncbi.nlm.nih.gov/pubmed/27247408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603799113
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