ING116070: A Study of the Pharmacokinetics and Antiviral Activity of Dolutegravir in Cerebrospinal Fluid in HIV-1–Infected, Antiretroviral Therapy–Naive Subjects

Background. Dolutegravir (DTG), a once-daily, human immunodeficiency virus type 1 (HIV-1) integrase inhibitor, was evaluated for distribution and antiviral activity in cerebrospinal fluid (CSF). Methods. ING116070 is an ongoing, single-arm, open-label, multicenter study in antiretroviral therapy–nai...

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Autori principali: Letendre, Scott L., Mills, Anthony M., Tashima, Karen T., Thomas, Deborah A., Min, Sherene S., Chen, Shuguang, Song, Ivy H., Piscitelli, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
HIV/AIDS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166983/
https://ncbi.nlm.nih.gov/pubmed/24944232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciu477
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