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The Sensitivity of Cancer Cells to Pheophorbide a-Based Photodynamic Therapy Is Enhanced by NRF2 Silencing

Photodynamic therapy (PDT) has emerged as an effective treatment for various solid tumors. The transcription factor NRF2 is known to protect against oxidative and electrophilic stress; however, its constitutive activity in cancer confers resistance to anti-cancer drugs. In the present study, we inve...

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Autori principali: Choi, Bo-hyun, Ryoo, In-geun, Kang, Han Chang, Kwak, Mi-Kyoung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165896/
https://ncbi.nlm.nih.gov/pubmed/25226504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107158
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