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The Sensitivity of Cancer Cells to Pheophorbide a-Based Photodynamic Therapy Is Enhanced by NRF2 Silencing

Photodynamic therapy (PDT) has emerged as an effective treatment for various solid tumors. The transcription factor NRF2 is known to protect against oxidative and electrophilic stress; however, its constitutive activity in cancer confers resistance to anti-cancer drugs. In the present study, we inve...

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Main Authors: Choi, Bo-hyun, Ryoo, In-geun, Kang, Han Chang, Kwak, Mi-Kyoung
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165896/
https://ncbi.nlm.nih.gov/pubmed/25226504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107158
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