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Activation of NRF2 by p62 and proteasome reduction in sphere-forming breast carcinoma cells

Cancer stem cells (CSCs) express high levels of drug efflux transporters and antioxidant genes, and are therefore believed to be responsible for cancer recurrence following chemo/radiotherapy intervention. In this study, we investigated the role of NF-E2-related factor 2 (NRF2), a master regulator o...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Ryoo, In-geun, Choi, Bo-hyun, Kwak, Mi-Kyoung
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480743/
https://ncbi.nlm.nih.gov/pubmed/25717032
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