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Involvement of NRF2 Signaling in Doxorubicin Resistance of Cancer Stem Cell-Enriched Colonospheres

Cancer stem cells (CSCs) are a subset of tumor cells, which are characterized by resistance against chemotherapy and environmental stress, and are known to cause tumor relapse after therapy. A number of molecular mechanisms underlie the chemoresistance of CSCs, including high expression levels of dr...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Ryoo, In-geun, Kim, Geon, Choi, Bo-hyun, Lee, Sang-hwan, Kwak, Mi-Kyoung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012872/
https://ncbi.nlm.nih.gov/pubmed/27582554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.145
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