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Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch

Over-expression of ornithine decarboxylase (ODC) is known to be involved in the epidermal carcinogenesis. However, the mechanism by which it enhances skin carcinogenesis remains undefined. Recently, role of stem cells localized in various epidermal compartments has been shown in the pathogenesis of...

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Detalhes bibliográficos
Main Authors: Arumugam, Aadithya, Weng, Zhiping, Chaudhary, Sandeep C., Afaq, Farrukh, Elmets, Craig A., Athar, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165545/
https://ncbi.nlm.nih.gov/pubmed/25094045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.07.129
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