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Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch

Over-expression of ornithine decarboxylase (ODC) is known to be involved in the epidermal carcinogenesis. However, the mechanism by which it enhances skin carcinogenesis remains undefined. Recently, role of stem cells localized in various epidermal compartments has been shown in the pathogenesis of...

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Bibliografische gegevens
Hoofdauteurs: Arumugam, Aadithya, Weng, Zhiping, Chaudhary, Sandeep C., Afaq, Farrukh, Elmets, Craig A., Athar, Mohammad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165545/
https://ncbi.nlm.nih.gov/pubmed/25094045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.07.129
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