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Adeno-Associated Virus Type 2 VP2 Capsid Protein Is Nonessential and Can Tolerate Large Peptide Insertions at Its N Terminus

Direct insertion of amino acid sequences into the adeno-associated virus type 2 (AAV) capsid open reading frame (cap ORF) is one strategy currently being developed for retargeting this prototypical gene therapy vector. While this approach has successfully resulted in the formation of AAV particles t...

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Detaylı Bibliyografya
Asıl Yazarlar: Warrington, Kenneth H., Gorbatyuk, Oleg S., Harrison, Jeffrey K., Opie, Shaun R., Zolotukhin, Sergei, Muzyczka, Nicholas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC416546/
https://ncbi.nlm.nih.gov/pubmed/15163751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6595-6609.2004
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