Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

Adeno-associated virus (AAV)-derived vectors are promising gene delivery systems, and a number of design strategies have been pursued to improve their performance. For example, genetic insertion of proteins into the capsid may be used to achieve vector retargeting, reduced immunogenicity, or to trac...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Judd, Justin, Wei, Fang, Nguyen, Peter Q, Tartaglia, Lawrence J, Agbandje-McKenna, Mavis, Silberg, Jonathan J, Suh, Junghae
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2012
Θέματα:
Methods - Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511673/
https://ncbi.nlm.nih.gov/pubmed/23629029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.46
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