Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

Adeno-associated virus (AAV)-derived vectors are promising gene delivery systems, and a number of design strategies have been pursued to improve their performance. For example, genetic insertion of proteins into the capsid may be used to achieve vector retargeting, reduced immunogenicity, or to trac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Judd, Justin, Wei, Fang, Nguyen, Peter Q, Tartaglia, Lawrence J, Agbandje-McKenna, Mavis, Silberg, Jonathan J, Suh, Junghae
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Methods - Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511673/
https://ncbi.nlm.nih.gov/pubmed/23629029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.46
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