Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding

The adeno-associated virus type 2 (AAV2) uses heparan sulfate proteoglycan (HSPG) as its primary cellular receptor. In order to identify amino acids within the capsid of AAV2 that contribute to HSPG association, we used biochemical information about heparin and heparin sulfate, AAV serotype protein...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Opie, Shaun R., Warrington, Jr., Kenneth H., Agbandje-McKenna, Mavis, Zolotukhin, Sergei, Muzyczka, Nicholas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12768018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6995-7006.2003
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