Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding

The adeno-associated virus type 2 (AAV2) uses heparan sulfate proteoglycan (HSPG) as its primary cellular receptor. In order to identify amino acids within the capsid of AAV2 that contribute to HSPG association, we used biochemical information about heparin and heparin sulfate, AAV serotype protein...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Opie, Shaun R., Warrington, Jr., Kenneth H., Agbandje-McKenna, Mavis, Zolotukhin, Sergei, Muzyczka, Nicholas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC156206/
https://ncbi.nlm.nih.gov/pubmed/12768018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6995-7006.2003
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