Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding

The adeno-associated virus type 2 (AAV2) uses heparan sulfate proteoglycan (HSPG) as its primary cellular receptor. In order to identify amino acids within the capsid of AAV2 that contribute to HSPG association, we used biochemical information about heparin and heparin sulfate, AAV serotype protein...

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Publicat a:	J Virol
Autors principals:	Opie, Shaun R., Warrington, Jr., Kenneth H., Agbandje-McKenna, Mavis, Zolotukhin, Sergei, Muzyczka, Nicholas
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2003
Matèries:	Virus-Cell Interactions
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12768018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6995-7006.2003
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