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CD8(+) Treg cells suppress CD8(+) T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection

Although Treg-cell-mediated suppression during infection or autoimmunity has been described, functions of Treg cells during highly pathogenic avian influenza virus infection remain poorly characterized. Here we found that in Foxp3-GFP transgenic mice, CD8(+) Foxp3(+) Treg cells, but not CD4(+) Foxp3...

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Detalhes bibliográficos
Main Authors: Zou, Qiang, Wu, Bing, Xue, Jia, Fan, Xiaoxu, Feng, Congcong, Geng, Shuang, Wang, Ming, Wang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165276/
https://ncbi.nlm.nih.gov/pubmed/24114149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343583
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