CD45(+)CD33(low)CD11b(dim) myeloid-derived suppressor cells suppress CD8(+) T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer

Myeloid-derived suppressor cells (MDSCs) are a prominent component of the pro-tumoral response. The phenotype of and mechanisms used by MDSCs is heterogeneous and requires more precise characterization in gastric cancer (GC) patients. Here, we have identified a novel subset of CD45(+)CD33(low)CD11b(...

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Publicado no:Cell Death Dis
Main Authors: Mao, Fang-yuan, Zhao, Yong-liang, Lv, Yi-pin, Teng, Yong-sheng, Kong, Hui, Liu, Yu-gang, Wu, Xiao-long, Hao, Chuan-jie, Chen, Weisan, Duan, Mu-bing, Han, Bin, Ma, Qiang, Wang, Ting-ting, Peng, Liu-sheng, Zhang, Jin-yu, Cheng, Ping, Su, Chong-yu, Fu, Xiao-long, Zou, Quan-ming, Guo, Gang, Guo, Xiao-lan, Zhuang, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037756/
https://ncbi.nlm.nih.gov/pubmed/29988030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0803-7
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