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Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8(+) T cell responses against a HBV DNA vaccine in mice

Interleukin-22 (IL-22) is mainly produced by activated Th1 cells, Th17 cells and NK cells and promotes anti-microbial defense, pro-inflammatory and tissue remodeling responses. However, its potential use as a vaccine adjuvant has not been tested. In this study, we tested if a DNA construct expressin...

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Detalhes bibliográficos
Main Authors: Wu, Bing, Zou, Qiang, Hu, Yanxin, Wang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906397/
https://ncbi.nlm.nih.gov/pubmed/23941891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26047
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