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Adverse Effects of Doxorubicin and Its Metabolic Product on Cardiac RyR2 and SERCA2A
The use of anthracycline chemotherapeutic drugs is restricted owing to potentially fatal cardiotoxic side effects. It has been hypothesized that anthracycline metabolites have a primary role in this cardiac dysfunction; however, information on the molecular interactions of these compounds in the hea...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164980/ https://ncbi.nlm.nih.gov/pubmed/25106424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093849 |
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