Ion channel gating in cardiac ryanodine receptors from the arrhythmic RyR2-P2328S mouse

Mutations in the cardiac ryanodine receptor Ca(2+) release channel (RyR2) can cause deadly ventricular arrhythmias and atrial fibrillation (AF). The RyR2-P2328S mutation produces catecholaminergic polymorphic ventricular tachycardia (CPVT) and AF in hearts from homozygous RyR2(P2328S/P2328S) (denote...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Salvage, Samantha C., Gallant, Esther M., Beard, Nicole A., Ahmad, Shiraz, Valli, Haseeb, Fraser, James A., Huang, Christopher L.-H., Dulhunty, Angela F.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550012/
https://ncbi.nlm.nih.gov/pubmed/31028179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.229039
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