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Calcium Activation of Ryanodine Receptor Channels—Reconciling RyR Gating Models with Tetrameric Channel Structure

Despite its importance and abundance of experimental data, the molecular mechanism of RyR2 activation by calcium is poorly understood. Recent experimental studies involving coexpression of wild-type (WT) RyR2 together with a RyR2 mutant deficient in calcium-dependent activation (Li, P., and S.R. Che...

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Detalhes bibliográficos
Main Authors: Zahradník, Ivan, Györke, Sándor, Zahradníková, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266604/
https://ncbi.nlm.nih.gov/pubmed/16260840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509328
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