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Calcium Activation of Ryanodine Receptor Channels—Reconciling RyR Gating Models with Tetrameric Channel Structure

Despite its importance and abundance of experimental data, the molecular mechanism of RyR2 activation by calcium is poorly understood. Recent experimental studies involving coexpression of wild-type (WT) RyR2 together with a RyR2 mutant deficient in calcium-dependent activation (Li, P., and S.R. Che...

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Autori principali: Zahradník, Ivan, Györke, Sándor, Zahradníková, Alexandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266604/
https://ncbi.nlm.nih.gov/pubmed/16260840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509328
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