Functional Selectivity of Allosteric Interactions within G Protein–Coupled Receptor Oligomers: The Dopamine D(1)-D(3) Receptor Heterotetramer

The dopamine D(1) receptor–D(3) receptor (D1R-D3R) heteromer is being considered as a potential therapeutic target for neuropsychiatric disorders. Previous studies suggested that this heteromer could be involved in the ability of D3R agonists to potentiate locomotor activation induced by D1R agonist...

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Hauptverfasser: Guitart, Xavier, Navarro, Gemma, Moreno, Estefania, Yano, Hideaki, Cai, Ning-Sheng, Sánchez-Soto, Marta, Kumar-Barodia, Sandeep, Naidu, Yamini T., Mallol, Josefa, Cortés, Antoni, Lluís, Carme, Canela, Enric I., Casadó, Vicent, McCormick, Peter J., Ferré, Sergi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164978/
https://ncbi.nlm.nih.gov/pubmed/25097189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093096
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