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Allosteric mechanisms within the adenosine A(2A)-dopamine D(2) receptor heterotetramer

The structure constituted by a G protein coupled receptor (GPCR) homodimer and a G protein provides a main functional unit and oligomeric entities can be viewed as multiples of dimers. For GPCR heteromers, experimental evidence supports a tetrameric structure, comprised of two different homodimers,...

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Détails bibliographiques
Publié dans:Neuropharmacology
Auteurs principaux: Ferré, Sergi, Bonaventura, Jordi, Tomasi, Dardo, Navarro, Gemma, Moreno, Estefanía, Cortés, Antonio, Lluís, Carme, Casadó, Vicent, Volkow, Nora D.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754196/
https://ncbi.nlm.nih.gov/pubmed/26051403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.05.028
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