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Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model
An increasing number of G protein-coupled receptors (GPCRs) have been reported to be expressed in the plasma membrane as dimers. Since most ligand binding data are currently fitted by classical equations developed only for monomeric receptors, the interpretation of data could be misleading in the pr...
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| Publicat a: | Pharmacol Res |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360119/ https://ncbi.nlm.nih.gov/pubmed/30472462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.11.032 |
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