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Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model

An increasing number of G protein-coupled receptors (GPCRs) have been reported to be expressed in the plasma membrane as dimers. Since most ligand binding data are currently fitted by classical equations developed only for monomeric receptors, the interpretation of data could be misleading in the pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmacol Res
Egile Nagusiak: Casadó-Anguera, Verònica, Moreno, Estefanía, Mallol, Josefa, Ferré, Sergi, Canela, Enric I., Cortés, Antoni, Casadó, Vicent
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360119/
https://ncbi.nlm.nih.gov/pubmed/30472462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.11.032
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