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Emerging Insights into the Mechanistic Link between α-Synuclein and Glucocerebrosidase in Parkinson's Disease
Mutations in the GBA1 gene, encoding the enzyme glucocerebrosidase, cause the lysosomal storage disorder, Gaucher disease (GD), and are associated with the development of Parkinson's disease (PD) and other Lewy body disorders. Interestingly, GBA1 variants are the most common genetic risk factor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164968/ https://ncbi.nlm.nih.gov/pubmed/24256245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130158 |
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