α-Synuclein Interacts with Glucocerebrosidase Providing a Molecular Link between Parkinson and Gaucher Diseases

The presynaptic protein α-synuclein (α-syn), particularly in its amyloid form, is widely recognized for its involvement in Parkinson disease (PD). Recent genetic studies reveal that mutations in the gene GBA are the most widespread genetic risk factor for parkinsonism identified to date. GBA encodes...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yap, Thai Leong, Gruschus, James M., Velayati, Arash, Westbroek, Wendy, Goldin, Ehud, Moaven, Nima, Sidransky, Ellen, Lee, Jennifer C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Protein Structure and Folding
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151053/
https://ncbi.nlm.nih.gov/pubmed/21653695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237859
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk