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Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity
Mutations in GBA, the gene encoding glucocerebrosidase, the lysosomal enzyme deficient in Gaucher disease increase the risk for developing Parkinson disease. Recent research suggests a relationship between glucocerebrosidase and the Parkinson disease-related amyloid-forming protein, α-synuclein; how...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552326/ https://ncbi.nlm.nih.gov/pubmed/23266198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.11.010 |
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