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Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders

Mutations in the gene encoding the lysosomal enzyme glucocerebrosidase, known to cause Gaucher disease (GD), are a risk factor for the development of Parkinson disease (PD) and related disorders. This association is based on the concurrence of parkinsonism and GD, the identification of glucocerebros...

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Main Authors: Goker-Alpan, Ozlem, Stubblefield, Barbara K., Giasson, Benoit I., Sidransky, Ellen
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352317/
https://ncbi.nlm.nih.gov/pubmed/20838799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0741-7
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