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The Role of Glucocerebrosidase Mutations in Parkinson Disease and Lewy Body Disorders

Mutations in the gene encoding glucocerebrosidase (GBA), the enzyme deficient in the lysosomal storage disorder Gaucher disease, are associated with the development of Parkinson disease and other Lewy body disorders. In fact, GBA variants are currently the most common genetic risk factor associated...

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Autors principals: Velayati, Arash, Yu, W. Haung, Sidransky, Ellen
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529411/
https://ncbi.nlm.nih.gov/pubmed/20425034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11910-010-0102-x
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