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Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells

Currently there are limited treatment options for corneal blindness caused by dysfunctional corneal endothelial cells. The primary treatment involves transplantation of healthy donor human corneal endothelial cells, but a global shortage of donor corneas necessitates other options. Conventional tiss...

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Detalhes bibliográficos
Main Authors: Zhu, Ying-Ting, Li, Fu, Han, Bo, Tighe, Sean, Zhang, Suzhen, Chen, Szu-Yu, Liu, Xin, Tseng, Scheffer C.G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164941/
https://ncbi.nlm.nih.gov/pubmed/25202030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404032
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