Knockdown of Both p120 Catenin and Kaiso Promotes Expansion of Human Corneal Endothelial Monolayers via RhoA-ROCK-Noncanonical BMP-NFκB Pathway

PURPOSE. To determine the signaling pathway involved in expanding contact-inhibited human corneal endothelial cells (HCECs) using p120 and Kaiso small interfering RNAs (siRNAs). METHODS. Expansion of HCEC monolayers on collagen IV in SHEM using p120 siRNA was optimized regarding various dosage, freq...

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Autori principali: Zhu, Ying-Ting, Han, Bo, Li, Fu, Chen, Szu-Yu, Tighe, Sean, Zhang, Suzhen, Tseng, Scheffer C. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2014
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954405/
https://ncbi.nlm.nih.gov/pubmed/24474278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13633
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