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Knockdown of Both p120 Catenin and Kaiso Promotes Expansion of Human Corneal Endothelial Monolayers via RhoA-ROCK-Noncanonical BMP-NFκB Pathway
PURPOSE. To determine the signaling pathway involved in expanding contact-inhibited human corneal endothelial cells (HCECs) using p120 and Kaiso small interfering RNAs (siRNAs). METHODS. Expansion of HCEC monolayers on collagen IV in SHEM using p120 siRNA was optimized regarding various dosage, freq...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Association for Research in Vision and Ophthalmology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954405/ https://ncbi.nlm.nih.gov/pubmed/24474278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13633 |
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