Recruitment of focal adhesion kinase and paxillin to β1 integrin promotes cancer cell migration via mitogen activated protein kinase activation

BACKGROUND: Integrin-extracellular matrix interactions activate signaling cascades such as mitogen activated protein kinases (MAPK). Integrin binding to extracellular matrix increases tyrosine phosphorylation of focal adhesion kinase (FAK). Inhibition of FAK activity by expression of its carboxyl te...

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Detaylı Bibliyografya
Asıl Yazarlar: Crowe, David L, Ohannessian, Arthur
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2004
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC416481/
https://ncbi.nlm.nih.gov/pubmed/15132756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-18
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