Recruitment of focal adhesion kinase and paxillin to β1 integrin promotes cancer cell migration via mitogen activated protein kinase activation

BACKGROUND: Integrin-extracellular matrix interactions activate signaling cascades such as mitogen activated protein kinases (MAPK). Integrin binding to extracellular matrix increases tyrosine phosphorylation of focal adhesion kinase (FAK). Inhibition of FAK activity by expression of its carboxyl te...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Crowe, David L, Ohannessian, Arthur
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC416481/
https://ncbi.nlm.nih.gov/pubmed/15132756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-18
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky