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Recruitment of focal adhesion kinase and paxillin to β1 integrin promotes cancer cell migration via mitogen activated protein kinase activation

BACKGROUND: Integrin-extracellular matrix interactions activate signaling cascades such as mitogen activated protein kinases (MAPK). Integrin binding to extracellular matrix increases tyrosine phosphorylation of focal adhesion kinase (FAK). Inhibition of FAK activity by expression of its carboxyl te...

詳細記述

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書誌詳細
主要な著者: Crowe, David L, Ohannessian, Arthur
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC416481/
https://ncbi.nlm.nih.gov/pubmed/15132756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-18
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