Recruitment of focal adhesion kinase and paxillin to β1 integrin promotes cancer cell migration via mitogen activated protein kinase activation

BACKGROUND: Integrin-extracellular matrix interactions activate signaling cascades such as mitogen activated protein kinases (MAPK). Integrin binding to extracellular matrix increases tyrosine phosphorylation of focal adhesion kinase (FAK). Inhibition of FAK activity by expression of its carboxyl te...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Crowe, David L, Ohannessian, Arthur
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2004
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC416481/
https://ncbi.nlm.nih.gov/pubmed/15132756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-18
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