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The BiP Cochaperone ERdj4 Is Required for B Cell Development and Function
ERdj4 is a BiP cochaperone regulated by the unfolded protein response to facilitate degradation of unfolded and/or misfolded proteins in the endoplasmic reticulum. As the unfolded protein response plays a critical role in B cell maturation and antibody production, ERdj4 gene trap mice were generated...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164662/ https://ncbi.nlm.nih.gov/pubmed/25222125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107473 |
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