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ERdj4 and ERdj5 Are Required for Endoplasmic Reticulum-associated Protein Degradation of Misfolded Surfactant Protein C

Mutations in the SFTPC gene associated with interstitial lung disease in human patients result in misfolding, endoplasmic reticulum (ER) retention, and degradation of the encoded surfactant protein C (SP-C) proprotein. In this study, genes specifically induced in response to transient expression of...

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Detalhes bibliográficos
Main Authors: Dong, Mei, Bridges, James P., Apsley, Karen, Xu, Yan, Weaver, Timothy E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397301/
https://ncbi.nlm.nih.gov/pubmed/18400946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-07-0674
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