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The BiP Cochaperone ERdj4 Is Required for B Cell Development and Function

ERdj4 is a BiP cochaperone regulated by the unfolded protein response to facilitate degradation of unfolded and/or misfolded proteins in the endoplasmic reticulum. As the unfolded protein response plays a critical role in B cell maturation and antibody production, ERdj4 gene trap mice were generated...

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Autori principali: Fritz, Jill M., Weaver, Timothy E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164662/
https://ncbi.nlm.nih.gov/pubmed/25222125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107473
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