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Synthesis and Characterization of Oligonucleotides Containing a Nitrogen Mustard Formamidopyrimidine Monoadduct of Deoxyguanosine

[Image: see text] N(5)-Substituted formamidopyrimidine adducts have been observed from the reaction of dGuo or DNA with aziridine containing electrophiles, including nitrogen mustards. However, the role of substituted Fapy-dGuo adducts in the biological response to nitrogen mustards and related spec...

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Bibliographische Detailangaben
Hauptverfasser: Christov, Plamen P., Son, Kyu-Jun, Rizzo, Carmelo J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164228/
https://ncbi.nlm.nih.gov/pubmed/25136769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx5002354
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