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Jak3-Independent Trafficking of the Common γ Chain Receptor Subunit: Chaperone Function of Jaks Revisited

Janus kinases (Jaks) play an essential role in cytokine signaling and have been reported to regulate plasma membrane expression of their cognate receptors. In this study, we examined whether Jak3 and the common γ chain (γ(c)) reciprocally regulate their plasma membrane expression. In contrast to int...

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書誌詳細
主要な著者: Hofmann, Sigrun R., Lam, Albert Q., Frank, Stephan, Zhou, Yong-Jie, Ramos, Haydeé L., Kanno, Yuka, Agnello, Davide, Youle, Richard J., O'Shea, John J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC416416/
https://ncbi.nlm.nih.gov/pubmed/15143194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.5039-5049.2004
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