Jak3-Independent Trafficking of the Common γ Chain Receptor Subunit: Chaperone Function of Jaks Revisited

Janus kinases (Jaks) play an essential role in cytokine signaling and have been reported to regulate plasma membrane expression of their cognate receptors. In this study, we examined whether Jak3 and the common γ chain (γ(c)) reciprocally regulate their plasma membrane expression. In contrast to int...

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Detalhes bibliográficos
Main Authors: Hofmann, Sigrun R., Lam, Albert Q., Frank, Stephan, Zhou, Yong-Jie, Ramos, Haydeé L., Kanno, Yuka, Agnello, Davide, Youle, Richard J., O'Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC416416/
https://ncbi.nlm.nih.gov/pubmed/15143194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.5039-5049.2004
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