Jak3-Independent Trafficking of the Common γ Chain Receptor Subunit: Chaperone Function of Jaks Revisited

Janus kinases (Jaks) play an essential role in cytokine signaling and have been reported to regulate plasma membrane expression of their cognate receptors. In this study, we examined whether Jak3 and the common γ chain (γ(c)) reciprocally regulate their plasma membrane expression. In contrast to int...

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Autors principals: Hofmann, Sigrun R., Lam, Albert Q., Frank, Stephan, Zhou, Yong-Jie, Ramos, Haydeé L., Kanno, Yuka, Agnello, Davide, Youle, Richard J., O'Shea, John J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC416416/
https://ncbi.nlm.nih.gov/pubmed/15143194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.5039-5049.2004
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