Jak3-Independent Trafficking of the Common γ Chain Receptor Subunit: Chaperone Function of Jaks Revisited

Janus kinases (Jaks) play an essential role in cytokine signaling and have been reported to regulate plasma membrane expression of their cognate receptors. In this study, we examined whether Jak3 and the common γ chain (γ(c)) reciprocally regulate their plasma membrane expression. In contrast to int...

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Bibliografiske detaljer
Main Authors: Hofmann, Sigrun R., Lam, Albert Q., Frank, Stephan, Zhou, Yong-Jie, Ramos, Haydeé L., Kanno, Yuka, Agnello, Davide, Youle, Richard J., O'Shea, John J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC416416/
https://ncbi.nlm.nih.gov/pubmed/15143194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.5039-5049.2004
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