Autophosphorylation of JAK2 on Tyrosines 221 and 570 Regulates Its Activity

The tyrosine kinase JAK2 is a key signaling protein for at least 20 receptors in the cytokine/hematopoietin receptor superfamily and is a component of signaling by insulin receptor and several G-protein-coupled receptors. However, there is only limited knowledge of the physical structure of JAK2 or...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Argetsinger, Lawrence S., Kouadio, Jean-Louis K., Steen, Hanno, Stensballe, Allan, Jensen, Ole N., Carter-Su, Christin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416404/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15143187/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.11.4955-4967.2004
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