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Autophosphorylation of JAK2 on Tyrosines 221 and 570 Regulates Its Activity
The tyrosine kinase JAK2 is a key signaling protein for at least 20 receptors in the cytokine/hematopoietin receptor superfamily and is a component of signaling by insulin receptor and several G-protein-coupled receptors. However, there is only limited knowledge of the physical structure of JAK2 or...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC416404/ https://ncbi.nlm.nih.gov/pubmed/15143187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.4955-4967.2004 |
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