Autophosphorylation of JAK2 on Tyrosines 221 and 570 Regulates Its Activity

The tyrosine kinase JAK2 is a key signaling protein for at least 20 receptors in the cytokine/hematopoietin receptor superfamily and is a component of signaling by insulin receptor and several G-protein-coupled receptors. However, there is only limited knowledge of the physical structure of JAK2 or...

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Autores principales: Argetsinger, Lawrence S., Kouadio, Jean-Louis K., Steen, Hanno, Stensballe, Allan, Jensen, Ole N., Carter-Su, Christin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC416404/
https://ncbi.nlm.nih.gov/pubmed/15143187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.4955-4967.2004
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