Risk of Pediatric Celiac Disease According to HLA Haplotype and Country

BACKGROUND: The presence of HLA haplotype DR3–DQ2 or DR4–DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG). METHODS: We studied 6403 children with HLA haplotype DR3–DQ2 or DR4–D...

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Autors principals: Liu, Edwin, Lee, Hye-Seung, Aronsson, Carin A., Hagopian, William A., Koletzko, Sibylle, Rewers, Marian J., Eisenbarth, George S., Bingley, Polly J., Bonifacio, Ezio, Simell, Ville, Agardh, Daniel
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163840/
https://ncbi.nlm.nih.gov/pubmed/24988556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1313977
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