Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort

OBJECTIVES: There are significant geographical differences in the prevalence and incidence of celiac disease that cannot be explained by HLA alone. More than 40 loci outside of the HLA region have been associated with celiac disease. We investigated the roles of these non-HLA genes in the developmen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sharma, Ashok, Liu, Xiang, Hadley, David, Hagopian, William, Liu, Edwin, Chen, Wei-Min, Onengut-Gumuscu, Suna, Simell, Ville, Rewers, Marian, Ziegler, Anette-G., Lernmark, Åke, Simell, Olli, Toppari, Jorma, Krischer, Jeffrey P., Akolkar, Beena, Rich, Stephen S., Agardh, Daniel, She, Jin-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807782/
https://ncbi.nlm.nih.gov/pubmed/27015091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152476
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